Sigrid Nachtergaele

Assistant Professor of Molecular, Cellular, and Developmental Biology

Sigrid Nachtergaele joins Yale’s Department of Molecular, Cellular, and Developmental Biology as Assistant Professor in January 2020. Her research focuses on new mechanisms of post-transcriptional gene expression regulation, primarily through chemical modifications on mRNA transcripts. She comes from The University of Chicago, where she was a Howard Hughes Medical Institute Fellow of the Damon Runyon Cancer Research Foundation. Her work has included discovering novel chemical modifications and uncovering the mechanisms by which those modifications are regulated and affect cellular function. Her current program expands on this work to continue the tool development required to study the regulation and dynamics of these modifications in the context of cells. She earned her Ph.D. from Stanford University, studying the molecular mechanisms by which sterols influence Hedgehog signaling.